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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN2
All Species:
12.42
Human Site:
Y635
Identified Species:
21.03
UniProt:
Q16513
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16513
NP_006247.1
984
112035
Y635
T
P
Q
S
G
L
E
Y
S
G
I
Q
E
L
E
Chimpanzee
Pan troglodytes
XP_001145367
984
112028
Y635
T
P
Q
S
G
L
E
Y
S
G
I
Q
E
L
E
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
G681
C
L
A
V
L
G
R
G
H
F
G
K
V
L
L
Dog
Lupus familis
XP_547295
1021
115999
Y672
I
P
Q
P
G
L
G
Y
S
G
I
R
E
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWW9
983
111611
C634
I
P
D
S
G
R
S
C
W
G
V
G
E
L
D
Rat
Rattus norvegicus
O08874
985
112050
C636
I
P
D
S
S
R
S
C
W
S
V
G
E
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
F663
T
I
P
Q
L
Q
D
F
R
F
V
A
V
L
G
Chicken
Gallus gallus
XP_422357
1013
114806
Y664
V
P
H
S
D
I
K
Y
T
N
I
R
E
P
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700704
970
110327
Q635
E
I
R
D
E
E
E
Q
F
H
F
S
L
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
V317
G
K
G
S
F
G
K
V
M
L
A
E
K
K
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
G390
V
L
G
K
G
S
F
G
K
V
M
L
A
E
R
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
H482
I
S
V
L
G
R
G
H
F
G
K
V
L
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
T805
P
Q
K
S
Q
T
S
T
S
A
K
H
K
K
R
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Q758
Q
Q
Q
Q
T
P
Q
Q
V
S
P
M
Y
Q
Q
Conservation
Percent
Protein Identity:
100
99.6
46.1
92.8
N.A.
94.6
92.6
N.A.
53.9
87
N.A.
76.4
N.A.
28.3
N.A.
27.6
48.4
Protein Similarity:
100
99.9
63.2
94.7
N.A.
97.2
95.3
N.A.
68.2
91.9
N.A.
85
N.A.
42.3
N.A.
43.7
61.3
P-Site Identity:
100
100
6.6
73.3
N.A.
40
33.3
N.A.
13.3
40
N.A.
6.6
N.A.
6.6
N.A.
6.6
20
P-Site Similarity:
100
100
13.3
80
N.A.
53.3
40
N.A.
33.3
66.6
N.A.
20
N.A.
26.6
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
27.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
45.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
8
8
8
8
0
0
% A
% Cys:
8
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
8
8
0
8
0
0
0
0
0
0
0
15
% D
% Glu:
8
0
0
0
8
8
22
0
0
0
0
8
43
8
36
% E
% Phe:
0
0
0
0
8
0
8
8
15
15
8
0
0
0
0
% F
% Gly:
8
0
15
0
43
15
15
15
0
36
8
15
0
0
15
% G
% His:
0
0
8
0
0
0
0
8
8
8
0
8
0
0
0
% H
% Ile:
29
15
0
0
0
8
0
0
0
0
29
0
0
0
0
% I
% Lys:
0
8
8
8
0
0
15
0
8
0
15
8
15
22
0
% K
% Leu:
0
15
0
8
15
22
0
0
0
8
0
8
15
58
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
8
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
8
43
8
8
0
8
0
0
0
0
8
0
0
8
0
% P
% Gln:
8
15
29
15
8
8
8
15
0
0
0
15
0
8
8
% Q
% Arg:
0
0
8
0
0
22
8
0
8
0
0
15
0
0
15
% R
% Ser:
0
8
0
50
8
8
22
0
29
15
0
8
0
0
0
% S
% Thr:
22
0
0
0
8
8
0
8
8
0
0
0
0
0
8
% T
% Val:
15
0
8
8
0
0
0
8
8
8
22
8
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
29
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _